In a randomized, blinded, dual center study across two European primate research facilities, we evaluated the immunogenicity and protective efficacy of a DNA prime-oropharyngeal ad
Lung adenosquamous carcinoma (ASC) is a rare and aggressive subtype. This exploratory study aimed to evaluate the real-world clinical, pathological, and survival outcomes of patien
Abstract Purpose Trophoblast cell surface antigen 2 (TROP2) is a glycoprotein expressed on epithelial tumor cells and therefore an established target for antibody-drug conjugates (
Radical resection for locally advanced differentiated thyroid cancer (DTC) is challenging and associated with significant morbidity. This study aimed to evaluate the efficacy and s
Immune evasion is a key driver of tumour evolution and a major barrier to effective cancer therapy, frequently arising through suppression of the cytosolic DNA-sensing cGAS–STING p
Summary Current treatment options for advanced kidney cancer rely on small molecules targeting tyrosine kinase inhibitors (TKI), hypoxia-inducible factor 2 alpha (HIF2α), and mamma
Breast cancer precision therapy faces drug delivery and response prediction challenges. Ultrasound micro/nanobubble platforms integrate theranostic functions but lack consistent ev
Background: Premature ovarian insufficiency (POI) is an important reproductive and public health concern among women of reproductive age.Limited evidence is available regarding its