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Amoebic Infections and Treatments · Journal article
BMC Pregnancy and Childbirth · August 31, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a single case report of a pregnant woman with connective tissue disease who developed pyogenic liver abscess complicated by sepsis and preeclampsia. The report documents clinical presentation, diagnosis, and recovery following antibiotics and preterm delivery but provides no evidence on incidence, risk factors, or treatment outcomes generalizable beyond this patient.
Single case report. A 25-year-old pregnant woman (G2P1) at 22 + 4 weeks gestation presenting with recurrent intractable fever. Serological, imaging, and microbiological investigations were performed; multidisciplinary consultation confirmed coexisting diagnoses. Delivery was by labor induction at 23 + 1 weeks.. Intervention: Antibiotics, hepatoprotective agents, immune modulation, and labor induction at 23 + 1 weeks gestation..
25-year-old G2P1 woman at 22 + 4 weeks gestation presented with recurrent intractable fever and was found to have coexisting connective tissue disease, pyogenic liver abscess, sepsis, and preeclampsia. Hepatic puncture culture identified Streptococcus pneumoniae as the causative pathogen. Labor was induced at 23 + 1 weeks gestation due to severe fetal growth restriction and uncontrolled maternal infection.
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This case highlights the atypical presentation and diagnostic complexity of liver abscess in immunocompromised pregnant women and underscores the value of integrated serological-imaging screening and multidisciplinary collaboration. However, as a single case, it cannot inform clinical decision-making or prevalence estimates without supporting series or cohort data.
A single case report documenting an unusual clinical presentation; describes occurrence and management but provides no comparative data, control group, or generalizable evidence of causation or treatment efficacy.
As stated by the source record.
Quoted from the source exactly as published.
This case highlights the atypical presentation and diagnostic complexity of liver abscess in immunocompromised pregnant women and underscores the value of integrated serological-imaging screening and multidisciplinary collaboration. However, as a single case, it cannot inform clinical decision-making or prevalence estimates without supporting series or cohort data.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Abstract Connective tissue disease (CTD) during pregnancy impairs innate and adaptive immune homeostasis and increases susceptibility to occult bacterial infection and subsequent sepsis. We report a 25-year-old G2P1 woman at 22 + 4 weeks of gestation presenting with recurrent intractable fever. Serological examinations showed elevated inflammatory indices, liver dysfunction, thrombocytopenia and positive autoimmune antibodies. Multimodal imaging revealed intrahepatic infectious lesions. Multidisciplinary consultation confirmed the coexistence of CTD, pyogenic liver abscess, sepsis and preeclampsia. The patient was treated with antibiotics, hepatoprotective agents and immune modulation. Considering severe fetal growth restriction and uncontrolled maternal infection, labor induction at 23 + 1 weeks gestation was performed. Hepatic puncture culture identified Streptococcus pneumoniae as the causative pathogen, and the patient achieved clinical recovery after targeted antimicrobial therapy. This case demonstrates the atypical manifestations and diagnostic difficulties of liver abscess in immunocompromised pregnant women. Early integrated serological-imaging screening and multidisciplinary collaboration are essential to optimize maternal and perinatal outcomes.
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