Loading
Otolaryngology and Infectious Diseases · Journal article
Animals · August 11, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a case series describing an atypical, prolonged outbreak of blackleg in 7 unvaccinated Nelore cattle managed with intensive medical and surgical intervention. Two animals survived following treatment including fluid therapy, antimicrobials, debridement, and wound care, departing from the typically acute fatal course; one survivor underwent partial hind-limb amputation and was discharged after 116 days. The report contributes descriptive evidence on rare prolonged blackleg manifestations and cardiac pathology but cannot establish efficacy of treatment or generalizability without controlled comparison.
Retrospective case series / outbreak report. Seven unvaccinated Nelore cattle from a single herd in São Paulo, Brazil. Diagnosis of Clostridium chauvoei infection confirmed by PCR, clinical examination, and necropsy findings.. Intervention: Intensive medical and surgical management including fluid therapy, systemic antimicrobial treatment, surgical debridement of necrotic tissues, drainage, and intensive wound care.. n = 7. School of Veterinary Medicine and Animal Science, University of São Paulo (FZEA-USP), Brazil; one herd..
Seven cattle showed clinical signs in the outbreak; one died before veterinary intervention Four animals were referred to a veterinary hospital and managed with intensive multimodal therapy Three of four hospitalized animals died despite treatment
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
This report documents an unusually prolonged blackleg presentation in cattle managed with intensive intervention, suggesting potential survival in selected cases despite typical acute lethality. However, the single-outbreak, uncontrolled nature precludes attributing survival to specific treatments; the findings warrant further documentation and controlled study to establish whether multimodal management improves outcomes.
Single-center outbreak case series describing atypical clinical presentation and management outcomes in 7 cattle; lacks control group and prospective design, but provides detailed clinical and pathological observations of rare prolonged disease course.
As stated by the source record.
Quoted from the source exactly as published.
This report documents an unusually prolonged blackleg presentation in cattle managed with intensive intervention, suggesting potential survival in selected cases despite typical acute lethality. However, the single-outbreak, uncontrolled nature precludes attributing survival to specific treatments; the findings warrant further documentation and controlled study to establish whether multimodal management improves outcomes.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Blackleg, caused by Clostridium chauvoei, is a severe infectious disease of cattle typically characterized by an acute or peracute course with rapid progression to death within 48 h after the onset of clinical signs. However, well-described reports of chronic or prolonged clinical evolution are rare. This study aimed to describe an outbreak with an atypical, prolonged course and to report the therapeutic management of affected animals. In March 2023, an outbreak occurred in an unvaccinated Nelore herd, with seven cattle showing clinical signs and one dying before veterinary intervention. Due to disease severity, four animals were referred to the Veterinary Hospital (HOVET) of the School of Veterinary Medicine and Animal Science, University of São Paulo (FZEA-USP), while others were managed on-farm. Clinical management included fluid therapy, systemic antimicrobial treatment, surgical debridement of necrotic tissues, drainage, and intensive wound care. Despite treatment, three animals died during hospitalization. One severely affected animal underwent partial amputation of a hind limb and survived, and it was discharged after 116 days of treatment. Diagnosis was confirmed by PCR, clinical examination, and necropsy findings. Overall, the clinical course observed differed from the typical acute presentation, with two animals surviving, suggesting that intensive medical and surgical management may improve outcomes in selected cases. Cardiac lesions were identified in necropsied animals, with exclusive involvement of the left ventricle, a finding that may warrant further investigation. This report highlights atypical manifestations of blackleg and contributes to the limited literature on prolonged cases.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.