Cardiogenic Shock · Observational Study

Prognostic Value Enhancement Of Sequential Organ Failure Assessment )SOFA( Score by Neutrophil-Lymphocyte Ratio and Red Cell Distribution Width in Cardiogenic Shock Patients.

ClinicalTrials.gov · August 19, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a planned observational study registered to examine whether neutrophil-lymphocyte ratio (NLR) and red cell distribution width (RDW) enhance the prognostic value of SOFA score in cardiogenic shock patients. No results are currently available; the study has not yet begun recruitment.

What was studied

Observational. Cardiogenic Shock; age from 18 Years. Intervention: cardiogenic shock patients. n = 150. 1 site: Egypt.

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

If results are published, clinicians may gain guidance on whether biomarker combinations (NLR, RDW) can improve risk stratification beyond SOFA score alone in acute cardiogenic shock. Pending completion and peer review.

Plain-language summary

This is a planned observational registry study with no results posted; enrollment has not yet begun, making it an early-stage descriptive investigation of biomarker associations.

Study design

As stated by the source record.

MethodsCohort model. Retrospective time perspective. Primary outcome measure: Number of patients with Higher NLR and RDW values who died With Cardiogenic Shock (assessed at through study completion, an average 6 months.)

DesignObservational

PopulationCardiogenic Shock; age from 18 Years

Sample size150

Interventioncardiogenic shock patients

Setting1 site: Egypt

Reported figures

Quoted from the source exactly as published.

Planned enrollment150

Primary outcome measureNumber of patients with higher NLR and RDW values who died with cardiogenic shock through study completion, an average 6 months

Study phaseObservational

Clinical bottom line

Caveats

This is a registry record; no results are reported and study recruitment has not yet begun.
Study design is observational without a comparator arm; no causal inference is possible.
Follow-up duration stated as 'average 6 months' but exact protocol timing is unclear from registry entry.
No baseline characteristics, inclusion/exclusion criteria, or outcome definitions are provided in the registry summary.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Observational design without control group; no randomization or blinding.

Directness

moderate

Directly examines prognostic biomarkers in cardiogenic shock but outcome is mortality, not intervention.

Consistency

insufficient

No results reported; consistency cannot be assessed from registry record alone.

Risk of bias

insufficient

Study not yet recruiting; no methodology detail available to assess bias risk.

Sample adequacy

moderate

Planned enrollment 150 participants; adequacy depends on effect size not yet known.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT07773597). This is a study registration, not published results. Lead sponsor: Sohag University. Recruitment status: NOT_YET_RECRUITING. Study type: OBSERVATIONAL. Enrollment: 150 participants (ESTIMATED). Conditions: Cardiogenic Shock. Primary outcome measures: Number of patients with Higher NLR and RDW values who died With Cardiogenic Shock , through study completion, an average 6 months.. Brief summary: Prognostic Value Enhancement Of Sequential Organ Failure Assessment )SOFA( Score by Neutrophil-Lymphocyte Ratio and Red Cell Distribution Width in Cardiogenic Shock Patients.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

NCT07773597Sohag UniversityCardiogenic Shock