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Life sciences · Journal article
International Journal of Drug Delivery Technology · October 21, 2026
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Hypertension is one of the most important modifiable risk factors for cardiovascular, cerebrovascular, renal, and metabolic morbidity.Although modern clinical guidelines define hypertension primarily through repeated blood pressure measurement and cardiovascular risk assessment, patient-to-patient variability in clinical presentation, lifestyle background, stress reactivity, metabolic status, body habitus, and therapeutic response remains a major challenge in long-term management.Ayurveda explains such inter-individual variability through the concepts of Prakriti and Dosha predominance, principally Vata, Pitta, and Kapha.The present review-based case study paper examines the comparative clinical relevance of Vata, Pitta, and Kapha predominance in hypertensive individuals using a structured academic format.The paper integrates contemporary hypertension literature with Ayurvedic constitutional theory, published Prakriti-related biomedical studies, and a proposed clinical assessment framework.The review suggests that Vata predominance may be clinically interpreted in relation to autonomic variability, anxiety, irregular lifestyle, sleep disturbance, and fluctuating blood pressure; Pitta predominance may correlate with heat, irritability, inflammatory tendency, strong metabolic drive, and stress-related vascular response; and Kapha predominance may be associated with obesity, sedentary behavior, dyslipidemia, insulin resistance, fluid retention, and sustained elevation of blood pressure.The study further proposes a systematic clinical model for evaluating hypertensive individuals according to conventional risk factors and Ayurvedic constitutional predominance.This integrative approach does not replace evidence-based hypertension diagnosis or pharmacological care, but may improve individualized counselling, lifestyle planning, diet selection, stress management, and preventive cardiometabolic care.Larger observational and interventional studies are required to validate the clinical significance of Dosha predominance in hypertension.