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Life sciences · Preprint
arXiv · October 2, 2026
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Large-scale pre-training has improved the generalization of neural operators across diverse PDEs. However, existing PDE foundation models still struggle with heterogeneous dynamics, where shared representations may cause knowledge interference, while mixture-of-experts (MoE) architectures suffer from increasing expert redundancy. We propose SPEAR, a spectral-disentangled MoE neural operator with knowledge-guided expert aggregation for large-scale PDE pre-training. SPEAR decouples latent features into low- and high-frequency components, enabling shared modeling of transferable dynamics and specialized learning of PDE-specific patterns. To address expert redundancy, we design a knowledge-guided expert aggregation strategy that measures expert similarity from dataset-specific learned knowledge and routing preferences, enabling the identification and consolidation of similar experts. Experiments on twelve PDE datasets and multiple downstream benchmarks demonstrate superior performance in pre-training, fine-tuning, and transfer learning. Furthermore, our aggregation strategy reduces the number of experts by 50\% while maintaining or improving prediction accuracy, achieving a balance between model efficiency and generalization for PDE foundation models.