Clinical Trials to Evaluate Neurophysiological and Neuropsychological Effects of a Mindfulness-based Intervention

Registry record from ClinicalTrials.gov (NCT06618339). This is a study registration, not published results. Lead sponsor: Universidad Autonoma de Baja California. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 19 participants (ACTUAL). Conditions: Anxiety Depression (Mild or Not Persistent). Interventions: BEHAVIORAL: Mindfulness-based intervention. Primary outcome measures: Neurophysiological measures , Pre-post intervention assessment, after 8 weeks. A follow-up measure will be recorded immidiatly after each intervention session, 8 weeks as well.; Mood measures , Pre-post intervention assessment, after 8 weeks.; Card Sorting Test , Pre-post intervention assessment, after 8 weeks.; Self directed signaling , Pre-post intervention assessment, after 8 weeks.; Stroop Test , Pre-post intervention assessment, after 8 weeks.; Working memory , Pre-post intervention assessment, after 8 weeks.; Gambling test , Pre-post intervention assessment, after 8 weeks.; Tower of Hanoi , Pre-post intervention assessment, after 8 weeks.; Metamemory , Pre-post intervention assessment, after 8 weeks.; Neuropsychological evaluation , Pre-post intervention assessment, after 8 weeks.; Neuropsychological measure , Pre-post intervention assessment, after 8 weeks.. Brief summary: Depression and anxiety are conditions with a high prevalence in the world population and youth are no exception. In developing countries it is reported that given the conditions of social disadvantage, anxiety and depression are higher, resulting in compromised psychological well-being and mental health. Therefore, treatments that help in the care and prevention of these disorders from youth are important. In the case of contemporary psychology, Mindfulness treatments have emerged as an alternative treatment for some of the symptoms of depression, anxiety and emotional discomfort, showing evidence of increased improvement in the overall quality of life. The project responds to global mental health demands and will provide the institution, as well as external collaborating institutions and society in general, with guidelines to carry out brief and effective interventions for these problems and will develop clinical evidence and technological tools for their analysis. Objective: To compare the neurophysiological effects by means of EEG signals and machine learning or deep learning techniques and neuropsychological effects of a brief treatment based on mindfulness-based intervention techniques as an alternative intervention for the reduction of anxiety and depression symptoms against the effects of psychoeducation groups and placebo group in young adults. Methodology: Factorial design of cases and controls according to the guidelines for randomized controlled trials CONSORT. Participants (n=125) will be randomized triple-blinded with neuropsychological and neurophysiological assessments. The results of the project will generate basic evidence on the condition of brain functioning at the neurophysiological level, its performance to perform processes of utmost relevance to solve daily life problems and psychological well-being, as well as support the development of techniques for specialists in behavioral analysis and mental health and engineering sciences for the creation and implementation of programs and strategies for the prevention, identification, care and evaluation of mental health and social well-being, with a scientific and community health approach.