Life sciences · Interventional Study
ClinicalTrials.gov · October 2, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT06038929). This is a study registration, not published results. Lead sponsor: Mayo Clinic. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 16 participants (ESTIMATED). Conditions: Depression, Epilepsy. Interventions: DEVICE: Vagal nerve stimulant. Primary outcome measures: Gastric emptying T1/2 , during 4 hour gastric emptying test; Gastric accommodation , during first 1 hour of gastric emptying test. Brief summary: The specific aim of this study is to compare simultaneous assessment of gastric emptying and gastric accommodation in response to a caloric meal In patients who have previously undergone activation of left cervical VNS for the treatment of medication-resistant depression. Our hypothesis is that cervical VNS increases gastric accommodation and accelerates gastric emptying compared to a bank of healthy control data.