Loading
Life sciences · Journal article
Obesity Facts · October 26, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Journal article.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Abstract Background and Objective: Due to high demand for metabolic and bariatric surgery, patients often face significant waiting periods before undergoing the procedure. This study aimed to investigate trends in weight and metabolic changes among patients with severe obesity awaiting surgery, given the potential impact of preoperative metabolic changes on perioperative outcomes. Methods: This retrospective cohort study included patients with severe obesity who had been waiting for metabolic and bariatric surgery for at least six months. Weight, body composition analysis parameters, and biochemical tests were recorded every six to eight weeks for these candidates. Results: Among the 2926 patients studied, the average age was 39.7 years, with 74.8% being women. The mean weight was 124.65 kg, while the mean BMI was 46.14 kg/m². Seventy-five percent of the patients had obesity-related comorbidities. Adjusted models based on generalized estimating equations (GEE) approach showed that weight, FBS, insulin, and TG have an increasing trend over time. Male sex was associated with significantly higher weight (+25.78 kg), FBS (+4.11 mg/dL), insulin (+8.47 µIU/mL), TG (+15.39 mg/dL), SGPT (+17.59 IU/L), and SGOT (+6.93 IU/L), as well as lower HDL (−3.89 mg/dL), and a small but statistically significant increase in BUN. Age showed small but significant effects, with increases linked to reduced weight, insulin, TG, and SGPT, but slightly higher FBS, LDL, HDL, and BUN values. Dyslipidemia was significantly associated with higher TG (+38.20 mg/dL), while type 2 diabetes mellitus was linked to large increases in FBS (+61.63 mg/dL) and TG (+18.04 mg/dL) and a decrease in LDL (−7.50 mg/dL). The presence of cardiovascular disease was related to higher insulin (+7.22 µIU/mL), but lower TG (−4.02 mg/dL) and LDL (−13.84 mg/dL). Conclusion: Lengthening the waiting time for surgery can lead to worsening glycolipid status and weight gain in patients. Therefore, if possible, reducing wait times or providing more regular and thorough nutritional and psychological consultations can improve metabolic conditions, resulting in better outcomes after surgery.