Life sciences · Preprint
arXiv · September 10, 2026
Raises a question worth testing. It does not answer one.
This is an unpublished computational methods paper presenting a neural operator learning approach for sampling from invariant measures of stochastic differential equations. The work is theoretical and algorithmic in nature, with preliminary experimental results on synthetic problems; it has not undergone peer review and does not address clinical or biological outcomes.
Preprint. Intervention: Amortized neural sampler combining operator learning with flow methods for sampling from invariant measures of SDEs, using Lagrangian trajectory sensors and cross attention. Compared with: MCMC.
Framework enables efficient sampling across families of SDEs by shifting computational cost to an initial training phase, after which new instances require only one encoder pass and a few ODE solver steps independent of mixing time Demonstrates competitive accuracy with substantial speedups over MCMC in slow-mixing regimes on 1D and 2D SDE families Achieves transfer learning across different sensor counts and demonstrates feasibility on a 64D interacting particle SDE where traditional grid approaches are infeasible
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The source did not state who this applies to in practice.
This is a methodological preprint proposing a novel computational framework without empirical validation against established baselines or clinical/scientific outcomes; it demonstrates feasibility on synthetic problems but lacks peer review and real-world application evidence.
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We introduce an amortized neural sampler that combines operator learning with flow methods for sampling. It maps SDE coefficient functions to pushforwards from a reference measure to the invariant measures, enabling efficient sampling across families of stochastic differential equations. Our framework shifts traditional sampling cost to an initial training phase, after which new SDE instances require only one encoder pass and a few ODE solver steps, independent of mixing time. To handle problems in high dimensions, we use Lagrangian trajectory sensors for the coefficient functions and cross attention in the architecture. We also theoretically establish the expressivity and resolution invariance of our framework. Experiments on 1D and 2D SDE families show competitive accuracy with substantial speedups over MCMC in regimes with slow mixing, transfer across sensor counts, and demonstration results on a 64D interacting particle SDE where traditional grid approaches are infeasible.
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