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Pre-habilitation exercise program / Breast Cancer · Interventional Study
ClinicalTrials.gov · August 20, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a prospective, multicenter randomized controlled trial protocol for a preoperative exercise intervention in women with luminal B or triple-negative breast cancer. No results have been posted to the registry; the record describes only the planned study design, enrollment target, and outcome measures.
Interventional, Randomized, Parallel, Open label, Treatment purpose. Breast Cancer; Female; age from 18 Years. Intervention: Personalized pre-habilitation exercise training program and…. Compared with: Lifestyle counseling — No Intervention. n = 126. 2 sites: Italy.
This is a prospective, multicenter randomized controlled trial protocol for a preoperative exercise intervention in women with luminal B or triple-negative breast cancer. No results have been posted to the registry; the record describes only the planned study design, enrollment target, and outcome measures.
Effect sizes, comparative efficacy, safety events, and secondary outcome measures are not available.
The source did not state who this applies to in practice.
This is a recruiting trial with no reported results; the registry record describes planned design and enrollment only, making it a prospective study protocol at the enrollment stage.
As stated by the source record.
Quoted from the source exactly as published.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07776951). This is a study registration, not published results. Lead sponsor: University of Milan. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 126 participants (ESTIMATED). Conditions: Breast Cancer. Interventions: BEHAVIORAL: Pre-habilitation exercise program. Primary outcome measures: Exercise capacity , Baseline and 6 months. Brief summary: PhActHealth is a multicenter randomized controlled trial enrolling women with newly diagnosed luminal B or triple-negative breast cancer (BC) who are candidates for neoadjuvant therapy. The study aims to investigate the effects of a preoperative, unsupervised exercise training program on exercise capacity, as well as on immune response, autonomic nervous system (ANS) regulation, cardiovascular health, and tumor aggressiveness prior to surgical removal. Participants are randomly assigned to either an intervention group or a control group. All patients receive lifestyle counseling, while those in the intervention group additionally follow a personalized aerobic and resistance exercise program throughout the neoadjuvant treatment period before surgery. The primary outcome is the improvement in exercise capacity. The secondary outcomes are tumor-specific and systemic responses to the intervention, evaluated by analyzing molecular, metabolic, and inflammatory markers, as well as clinical and functional parameters.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.