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Adrenal Insufficiency / Growth Disorder / Endocrine Diseases · Observational Study
ClinicalTrials.gov · August 7, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a registry record describing an ongoing observational study recruiting children aged 3 months to 18 years with known or suspected endocrine or metabolic disorders, along with family members, to characterize disease inheritance and identify genetic contributions. No results are posted in this registry record; the study is actively recruiting and has not yet reported outcomes.
Observational. Adrenal Insufficiency, Growth Disorder, Endocrine Diseases, Metabolic Disease, Bone Diseases, Metabolic; age from 3 Months; to 100 Years. Intervention: Case Only. n = 15,000. 1 site: United States.
This is a registry record describing an ongoing observational study recruiting children aged 3 months to 18 years with known or suspected endocrine or metabolic disorders, along with family members, to characterize disease inheritance and identify genetic contributions. No results are posted in this registry record; the study is actively recruiting and has not yet reported outcomes.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
This registry study does not yet provide clinical evidence on treatment efficacy or diagnostic accuracy; it is a recruitment and characterization effort. Clinicians should note that results are not available in this record.
This is an ongoing observational registry study with no results reported; it describes a recruitment effort to characterize endocrine and metabolic disorders in children and identify genetic contributions.
As stated by the source record.
Quoted from the source exactly as published.
This registry study does not yet provide clinical evidence on treatment efficacy or diagnostic accuracy; it is a recruitment and characterization effort. Clinicians should note that results are not available in this record.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT02769975). This is a study registration, not published results. Lead sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD). Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 15000 participants (ESTIMATED). Conditions: Adrenal Insufficiency, Growth Disorder, Endocrine Diseases, Metabolic Disease, Bone Diseases, Metabolic. Primary outcome measures: Provide an option for patients with unusual or challenging endocrine or metabolic conditions, who may or may not be eligible for an existing research protocol, to be evaluated at NIH. , Baseline; Recruit a diverse population of pediatric subjects with a known or suspected endocrine or metabolic disorder in order to provide NICHD investigators and trainees with hands-on experience related to the diagnosis, management, treatment, and follo... , Baseline. Brief summary: Background: Endocrine glands give off hormones. Researchers want to learn more about the disorders that affect these glands in children. These disorders might be caused by changes in genes. Genes contain DNA, which is the blueprint of how a cell works. Researchers want to identify the genes involved in endocrine and metabolic disorders. This might help develop new ways to diagnose and treat the disorders. Objective: To study the inheritance of endocrine or metabolism disorders. Eligibility: Children ages 3month-18 with known or suspected endocrine or metabolism disorders. Family members ages 3months-100. They may participate in the DNA part of the study. Design: Participants will be screened with a review of their medical records. Their parents or guardians will allow the records to be released. Participants will have a clinic visit. This may include a physical exam and medical history. Parents or guardians will give their consent for the study. Participants may have tests, surgery, or other procedures to help diagnose or treat their condition. These could include: Blood, urine, and saliva tests Growth hormone test Pituitary and adrenal function tests Picture of chromosomes Imaging tests. These may include X-ray, ultrasound, scans, or a skeletal survey. Genetic tests Sleep study Medical photographs If surgery is done, a tissue sample will be taken. Participants may have follow-up visits for diagnosis and treatment. Participating relatives will have one visit. This will include medical history and blood and saliva tests. The blood and saliva will be used for DNA testing. ...
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.