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Dexamethasone 6 mg Every 12 Hours / Maternal Infection During Pregnancy / Premature Birth · Observational Study
ClinicalTrials.gov · August 14, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a completed observational study registration comparing two antenatal dexamethasone doses in pregnant women at risk of preterm delivery. No results have been posted to the registry. Clinical conclusions cannot be drawn from this record alone.
Observational. Premature Birth, Neonatal Hypoglycemia, Maternal Infection During Pregnancy, Neurodevelopmental Disorder of Foetus, Respiratory Distress Syndrome (RDS), Necrot…; age from 26 Weeks; to 36 Weeks. Intervention: Dexamethasone 12 mg Every 12 Hours; Dexamethasone 6 mg Every 12 Hours. Compared with: Dexamethasone 6 mg every 12 hours for 48 hours (lower dose given to pregnant women at risk of preterm birth).. n = 200. 1 site: Indonesia.
This is a completed observational study registration comparing two antenatal dexamethasone doses in pregnant women at risk of preterm delivery. No results have been posted to the registry. Clinical conclusions cannot be drawn from this record alone.
Power calculation, effect size, and safety analyses not described in the registration.
Until results are published, this registry record cannot inform clinical practice. Clinicians should await peer-reviewed publication to evaluate whether dose differences affect ventilation duration, NICU length of stay, or safety.
This is a completed observational study with no posted results; the registry record describes planned analyses only, making it unsuitable for clinical inference until results are published.
As stated by the source record.
Quoted from the source exactly as published.
Until results are published, this registry record cannot inform clinical practice. Clinicians should await peer-reviewed publication to evaluate whether dose differences affect ventilation duration, NICU length of stay, or safety.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07765329). This is a study registration, not published results. Lead sponsor: Stella Maris Women and Children Hospital. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 200 participants (ACTUAL). Conditions: Premature Birth, Neonatal Hypoglycemia, Maternal Infection During Pregnancy, Neurodevelopmental Disorder of Foetus, Respiratory Distress Syndrome (RDS), Necrotizing Enterocolitis (NEC), Intraventricular Hemorrhage Neonatal, Neonatal Sepsis, Intraventricular Hemorrhage (IVH), Neonatal Respiratory Distress Syndrome. Interventions: DRUG: Dexamethasone 12 mg Every 12 Hours; DRUG: Dexamethasone 6 mg Every 12 Hours. Primary outcome measures: Duration of Mechanical Ventilation Support , From initiation of mechanical ventilation until discontinuation of mechanical ventilation, assessed up to NICU discharge or 12 weeks after birth, whichever occurred first. Brief summary: The goal of this observational study was to compare two doses of dexamethasone given to pregnant women at risk of preterm birth. Dexamethasone is a medicine used before birth to help a baby's lungs mature. This study looked at preterm babies born between 26 and 36 weeks of pregnancy. Researchers compared babies whose mothers received dexamethasone 12 mg every 12 hours for 48 hours with babies whose mothers received dexamethasone 6 mg every 12 hours for 48 hours. The main questions this study aimed to answer were: * Did the higher dose of dexamethasone help preterm babies need breathing support for a shorter time? * Did the higher dose help shorten the babies' stay in the Neonatal Intensive Care Unit (NICU)? * Was the higher dose as safe as the lower dose for babies and mothers? Researchers reviewed medical records from Stella Maris Women's and Children's Hospital from January 2018 to January 2023. They looked at neonatal outcomes, including breathing support, respiratory distress syndrome, length of NICU stay, low blood sugar in babies, infection in mothers, and developmental problems at 24 months.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.