Loading
Life sciences · Journal article
Jundishapur Journal of Natural Pharmaceutical Products · October 14, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Journal article.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Background: Antimicrobial resistance (AMR) has emerged as a major global public health challenge because of its increasing prevalence, which is largely driven by the inappropriate and excessive use of antibiotics. This problem has renewed scientific interest in medicinal plants, which are a rich source of bioactive metabolites and have been used for centuries in traditional medicine to treat infectious diseases. Objectives: To evaluate and compare the antimicrobial activities of ethanol extracts of different organs of selected medicinal plants against reference microorganisms and clinically isolated bacterial and fungal pathogens. Methods: Ethanol extracts of different parts of 21 medicinal plants belonging to several botanical families were tested using the broth microdilution method. Antimicrobial activity was assessed by determining the minimum inhibitory concentration (MIC) values against the quality control strains and the corresponding clinical isolates. Results: The tested extracts exhibited antimicrobial activity, with MIC values ranging from 8 to > 128 µg/mL against quality control strains of Escherichia coli, Klebsiella pneumoniae, Bacillus subtilis, Enterococcus faecalis, Staphylococcus aureus, Candida albicans, Candida krusei, and their isolated strains. Among the tested samples, the flower extract of Alcea biennis showed the strongest antibacterial activity, with MIC values of 8 µg/mL against the quality control strains of E. coli, B. subtilis, and E. faecalis and 16 µg/mL against the clinical strains. The herb extract of Cistus creticus also showed strong antibacterial activity against the reference strains of E. coli and S. aureus, whereas the herb extract of Lamium purpureum inhibited the quality control strain of S. aureus, with an MIC value of 8 µg/mL. Conclusions: Among the investigated medicinal plants, A. biennis and C. creticus exhibited notable antimicrobial activity. These results support further phytochemical characterization and pharmacological evaluation of these species as promising sources of novel antimicrobial compounds.