Loading
Life sciences · Observational Study
ClinicalTrials.gov · October 21, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Observational Study.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07476703). This is a study registration, not published results. Lead sponsor: Danderyd Hospital. Recruitment status: ACTIVE_NOT_RECRUITING. Study type: OBSERVATIONAL. Enrollment: 1400 participants (ESTIMATED). Conditions: Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency, Heart Failure, Pulmonary Disease, Chronic Obstructive (COPD), Steatohepatitis, Inflammation Biomarkers, Lipid Profile, Oral Microbiota, MASLD - Metabolic Dysfunction-Associated Steatotic Liver Disease, Metabolic Associated-dysfunction Steatohepatitis (MASH). Interventions: DIAGNOSTIC_TEST: Coronary computer tomography (CCTA); DIAGNOSTIC_TEST: Echocardiograhy and aortic ultrasound; DIAGNOSTIC_TEST: Liver elastography; DIAGNOSTIC_TEST: Arterial stiffness. Primary outcome measures: Diagnostic Performance of Machine Learning Analysis of Finger Photoplethysmography for Detection of Coronary Artery Disease (CAD-RADS ≥2) , Typically within 1 months of enrollment.; Long-Term Incident Major Adverse Renal and Cardiovascular Events (MARCE) , 3-8 years; Immune Activation Biomarkers and Prevalent Atherosclerotic Cardiovascular Disease , Typically within 1 months of enrollment; Lipid Mediator Profiles and Prevalent Atherosclerotic Cardiovascular Disease , Typically within 1 months of enrollment; Correlation Between Oral Microbiota Composition and Prevalent Coronary Artery Disease , Typically within 1 months of enrollment; Prevalence of Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD) , Typically within 1 months of enrollment; Prevalence of Abdominal Aortic Aneurysm , Typically within 1 months of enrolment. Brief summary: The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018. The study is a collaborative effort among six university hospitals across Sweden. A follow-up study, SCAPIS 2, is conducted for half of the original participants. In Stockholm, 2,500 individuals will be re-examined at Danderyd University Hospital and Karolinska Institutet. SCAPIS 2 includes a core set of examinations involving blood sampling, questionnaires, and imaging. In addition to these, complementary local investigations are conducted to enable more detailed research questions. This protocol describes the additional studies conducted in the Stockholm cohort. All complementary assessments aim to identify risk factors for current and future lung, liver, and cardiovascular diseases.: EXTENDED SAMPLING: Saliva and Blood Samples with Blood Cell Isolation. EXTENDED QUESTIONNAIRES: Dyspnea, Sleep, Respiratory Infections, and Dental Health. EXTENDED IMAGING AND PHYSIOLOGICAL MEASUREMENTS Cardiac Ultrasound and Abdominal Aortic Measurements. Liver Elastography. Vascular Stiffness by cuff-based pulse wave analysis and Photoplethysmography (PPG). Valvular and Vascular Calcification by CT imaging.