Life sciences · Preprint
arXiv · September 22, 2026
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Causal inference guides operational and managerial decisions but remains challenging in high-dimensional panel or tensor settings, where decisions may depend on the joint conditional distribution of missing control outcomes. We develop \emph{Counterfactual Tucker Diffusion} (\CFTDiff), which integrates the treatment mask and latent Tucker structure into conditional diffusion to recover this distribution given observed control outcomes through efficient nonlinear score learning in a low-dimensional core. The masked Tucker score preserves dependence across tensor modes while reducing the dimension of nonlinear score learning from the product of mode dimensions to the much smaller product of Tucker ranks. We establish high-probability error bounds for conditional score estimation that depend on the Tucker ranks, largest mode dimension, and the factor-strength-adjusted number of missing outcomes, and show how these bounds translate into recovery guaranties for the conditional distribution of the missing control outcomes. Across missing rates, simulations show more accurate point recovery than common causal panel and matrix/tensor completion methods; comparisons with nested diffusion specifications further demonstrate the gains from masked conditioning and Tucker dimension reduction. In Norway's iFlex experiment, \CFTDiff recovers missing outcomes more accurately than competing methods; when applied to causal analysis, its estimated conditional distributions yield counterfactual prediction intervals and target-attainment probabilities, allowing pricing interventions to be evaluated by demand-reduction magnitude and reliability.