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Life sciences · Observational Study
ClinicalTrials.gov · September 29, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT07351149). This is a study registration, not published results. Lead sponsor: Uppsala University. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 2000 participants (ESTIMATED). Conditions: Acute Kidney Injury. Primary outcome measures: Incidence of postoperative AKI , Within 7 postoperative days. Brief summary: This project aims to conduct an international, prospective, multicentre, observational study to determine the incidence of Postoperative Acute Kidney Injury (PO-AKI) in hospitalized children after noncardiac surgery. Urinary biomarkers are intended to be evaluated as predictors of PO-AKI in the same subjects. The study employs modern standardized classifications for AKI to comprehensively address the issue of PO-AKI in children. Describing the incidence and identifying risk factors for PO-AKI will play a crucial role in developing preventive strategies aimed at reducing associated mortality and morbidity. Furthermore, investigating the relationship between urinary biomarkers of renal injury and PO-AKI will provide valuable insights into assessing postoperative renal function in paediatric patients, especially when repeated blood sampling is not feasible.