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Dialysis and Renal Disease Management / Parathyroid Disorders and Treatments / Chronic Kidney Disease and Diabetes · Journal article
Eastern Medical College Journal · August 11, 2026
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This single-centre cross-sectional study of 53 obese patients in Bangladesh reports a high prevalence of renal dysfunction: 43.4% with reduced eGFR and 58.5% with albuminuria, with obesity-related glomerulopathy as the most common diagnosis (26.4%). The findings are descriptive and lack a comparator group, so they establish prevalence in this setting but cannot determine the strength of the obesity–renal disease association or guide clinical practice independently.
Prospective cross-sectional study. Adult obese patients (BMI ≥30 kg/m²) attending Eastern Medical College and Hospital, Cumilla, Bangladesh; no explicit exclusion criteria reported.. n = 53. Eastern Medical College and Hospital, Cumilla, Bangladesh.
43.4% of obese patients had reduced eGFR 58.5% of obese patients had albuminuria 26.4% had obesity-related glomerulopathy as the most common diagnosis
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The findings document a substantial burden of renal disease in obese populations in this setting and support the case for renal screening in obese patients. However, the cross-sectional design and small, purposively sampled cohort limit generalizability; the results should be confirmed in larger, population-based or case–control studies before informing routine practice guidelines.
Single-centre, small prospective cross-sectional study (n=53) with no comparator group; describes prevalence of renal findings in an obese population but lacks the design rigour and sample size to establish causation or guide practice change.
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The findings document a substantial burden of renal disease in obese populations in this setting and support the case for renal screening in obese patients. However, the cross-sectional design and small, purposively sampled cohort limit generalizability; the results should be confirmed in larger, population-based or case–control studies before informing routine practice guidelines.
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Background: The global obesity epidemic is a major independent risk factor for chronic kidney disease (CKD) via hemodynamic, metabolic, and inflammatory pathways. However, data on its specific renal manifestations within Bangladeshi tertiary care populations remains scarce, highlighting a critical need for localized clinical assessment. The objectives of this study were to assess the spectrum and frequency of renal diseases associated with obesity among patients attending a tertiary care hospital in Bangladesh. Materials and Methods: A prospective cross-sectional study was conducted at Eastern Medical College and Hospital, Cumilla, from July 2023 to June 2024. A purposive sample of 53 adult obese patients (BMI≥30 kg/m²) was enrolled. Participants underwent detailed clinical evaluation and laboratory investigations, including serum creatinine, estimated glomerular filtration rate (eGFR), urine albumin-creatinine ratio (UACR), and ultrasonography. Statistical analyses were performed using SPSS version 23.0. Results: The study of 53 obese patients revealed a high burden of renal disease: 43.4% had reduced eGFR and 58.5% had albuminuria. Obesity-related glomerulopathy was the most common diagnosis (26.4%). A significant association was found between higher BMI class and increased albuminuria prevalence (p=0.007). Participants with both hypertension and diabetes had a significantly higher rate of reduced eGFR (p=0.032). Conclusion: This study confirms the high prevalence of renal dysfunction in obese individuals, strongly linked to BMI severity and comorbidities. Obesity must be recognized as a major renal risk factor, necessitating routine renal screening and targeted public health interventions for weight management. Eastern Med Coll J. 2026; 11 (1): 26-30
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