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Life sciences · Journal article
The Professional Medical Journal · September 1, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a single-centre, cross-sectional survey documenting that 71.0% of 193 untreated women with DSM-5-diagnosed major depressive disorder report sexual dysfunction on the FSFI. The study is descriptive and observational, establishing frequency and demographic associations but not causality or the magnitude of excess risk attributable to depression alone.
Analytical cross-sectional study. Married women aged 18–45 years with untreated Major Depressive Disorder diagnosed per DSM-5 criteria, not currently on antidepressants.. n = 193. Outpatient department of Psychiatry and Behavioral Sciences, DHQ Hospital, Faisalabad Medical University (single centre, Pakistan)..
Sexual dysfunction present in 137 of 193 women (71.0%) Lowest FSFI domain scores in desire (2.8 ± 1.1) and arousal (3.1 ± 1.3) Significant association with older age (p = 0.021), longer marriage duration (p = 0.008), higher parity (p = 0.014), and cesarean delivery (p = 0.032)
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
Clinicians should recognise that sexual dysfunction is common in untreated depression; however, this study does not quantify the excess risk attributable to depression versus other demographic or reproductive factors, nor does it measure improvement with treatment.
A single-centre cross-sectional survey of untreated depression and sexual dysfunction without a comparator group; descriptive design with real findings but no causal inference capacity or control arm.
As stated by the source record.
Quoted from the source exactly as published.
Clinicians should recognise that sexual dysfunction is common in untreated depression; however, this study does not quantify the excess risk attributable to depression versus other demographic or reproductive factors, nor does it measure improvement with treatment.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Objective: To determine the frequency of sexual dysfunction among married women with untreated Major Depressive Disorder (MDD). Study Design: Analytical Cross sectional study. Period: June 2025 to December 2025. Setting: Outpatient department of Psychiatry and Behavioral Sciences, DHQ Hospital, Faisalabad Medical University. Methods: Total 193 married women aged 18–45 years, diagnosed with MDD per DSM-5 criteria and not on antidepressants, were enrolled using non-probability consecutive sampling. Sexual function was assessed using Female Sexual Function Index (FSFI), with a total score ≤26 indicating dysfunction. Data were analyzed using SPSS version 23.0; chi-square tests were applied to examine associations, with p ≤ 0.05 considered significant. Results: The mean age of participants was 31.4 ± 6.2 years. Sexual dysfunction was present in 137 women (71.0%), with the lowest FSFI domain scores in desire (2.8 ± 1.1) and arousal (3.1 ± 1.3). Significant associations were found between sexual dysfunction and older age (p = 0.021), longer marriage duration (p = 0.008), higher parity (p = 0.014), and cesarean delivery (p = 0.032). Employment status showed no significant association (p = 0.217). Conclusion: Female sexual dysfunction was frequent in women with untreated depression, particularly affecting desire and arousal, and is significantly influenced by reproductive and demographic factors.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.