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Suicidal / Suicidal Ideation / Suicidal Ideation and Behavior · Interventional Study
ClinicalTrials.gov · September 9, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a registry record of an active pilot study evaluating the feasibility and acceptability of intramuscular ketamine for acute suicidal distress in an emergency department setting. No results are yet reported. The study is designed to inform procedures and identify the patient population presenting with suicidal distress, not to establish efficacy or safety.
Interventional, Single Group, Open label, Other purpose. Suicidal, Suicidal Ideation, Suicidal Ideation and Behavior, Depression / Major Depressive Disorder; age from 18 Years. Intervention: Dosing Cohort: ketamine. n = 8. 1 site: United States.
This is a registry record of an active pilot study evaluating the feasibility and acceptability of intramuscular ketamine for acute suicidal distress in an emergency department setting. No results are yet reported. The study is designed to inform procedures and identify the patient population presenting with suicidal distress, not to establish efficacy or safety.
Primary outcomes are process measures (ED time, survey acceptability) not clinical efficacy or safety endpoints.
This pilot cannot yet inform clinical practice. Results, when available, will indicate only whether ketamine administration is feasible and acceptable to staff and patients in an ED setting, not whether it reduces suicidal distress or improves clinical outcomes.
This is an active pilot feasibility study with no results reported; the registry record describes planned enrollment of 8 participants and surrogate endpoints (ED time, survey scores) rather than clinical outcomes.
As stated by the source record.
Quoted from the source exactly as published.
This pilot cannot yet inform clinical practice. Results, when available, will indicate only whether ketamine administration is feasible and acceptable to staff and patients in an ED setting, not whether it reduces suicidal distress or improves clinical outcomes.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07810023). This is a study registration, not published results. Lead sponsor: Endeavor Health. Recruitment status: ENROLLING_BY_INVITATION. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 8 participants (ESTIMATED). Conditions: Suicidal, Suicidal Ideation, Suicidal Ideation and Behavior, Depression / Major Depressive Disorder. Interventions: DRUG: Ketamine (0.5 mg/kg). Primary outcome measures: Difference in time spent in the ED for dosing participants vs non-dosing patients , Up to 7 Days; Average dosing participants' scores of investigator-developed feasibility and acceptability survey. , Up to 7 days; Average ER personnel score of investigator-developed feasibility and acceptability survey , Up to 7 days. Brief summary: This pilot study aims to evaluate the feasibility and acceptability of administering intramuscular ketamine for the acute reduction of suicidal distress during psychiatric boarding at the Evanston Hospital ED. This study also aims to identify and describe the broader patient population who present to the Evanston Hospital ED in suicidal distress. This study includes several cohorts. A small (n=8) dosing cohort will receive an IM injection of ketamine. Additionally, an ED staff cohort and a research staff cohort can complete optional surveys to provide feedback about study procedures. Lastly, a chart review will be conducted after the completion of the study to determine the volume and patterns of patients who present to Evanston Hospital ED in suicidal distress.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.