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Life sciences · Interventional Study
ClinicalTrials.gov · September 17, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07819045). This is a study registration, not published results. Lead sponsor: University of Oklahoma. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 42 participants (ACTUAL). Conditions: Metastatic Invasive Breast Cancer, Metastatic Invasive Gynecologic Cancer. Interventions: BEHAVIORAL: Acceptance- and Mindfulness-Based Intervention. Primary outcome measures: Semi-structured Interviews , 9 weeks; Perceived ease of use , Week 9; Perceived Usefulness , Week 9; Enjoyability , Week 9; Enjoyability - Interest/Enjoyment Subscale , Week 9; Feasibility of the Program - Study Retention , Week 9; Feasibility of the Program - Adherence , Week 9; Feasibility of Collecting Biological Samples , Week 9. Brief summary: Physical activity can improve health-related quality of life among people receiving cancer treatment. Yet, chemotherapy imposes considerable barriers to maintaining an active lifestyle. Emotion regulation-based approaches based on principles from Self-Determination Theory (SDT) and Acceptance and Commitment Therapy (ACT) may help people engage in physical activity despite treatment-related challenges. We aimed to develop and conduct a proof of concept study among people initiating chemotherapy for breast and gynecologic cancers to develop and assess the feasibility and acceptability of a novel, mobile health physical activity intervention that drew from SDT and ACT principles.