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Life sciences · Preprint
arXiv · October 21, 2026
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We analyze the problem of estimating univariate Gaussian mixture densities using the nonparametric maximum likelihood estimator (NPMLE) based on $n$ independent and identically distributed samples. We show that the unconstrained NPMLE achieves the minimax optimal rate $\log(n)/n$ in squared Hellinger distance, when the true mixing measure is sub-Gaussian. In addition, we show that when the true mixing measure has compact support, the NMPLE constrained to a compact interval also achieves the minimax optimal rate, which is slightly faster and of order $\log(n)/(n \log \log n)$. Our proof consists of sharply characterizing the local Hellinger bracketing entropy of the class of finite Gaussian mixtures. One of our key technical innovations is to sharply bound the $L^2$ bracketing entropy of balls of bounded-degree polynomials, which may be of independent interest. As an application, we establish the regret-optimality of $g$-modeling procedures based on the NPMLE in the Gaussian Empirical Bayes problem with bounded priors.