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Life sciences · Observational Study
ClinicalTrials.gov · October 14, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT07667699). This is a study registration, not published results. Lead sponsor: Kartal City Hospital. Recruitment status: ENROLLING_BY_INVITATION. Study type: OBSERVATIONAL. Enrollment: 200 participants (ESTIMATED). Conditions: Healthy, Perimenopausal Depression, Menopausal Complaints, Bone Mineral Density, Sarcopenia, Sleep Quality, Quality of Life. Primary outcome measures: Physical Functional Performance Score assessed by 30-Second Chair Stand Test and Hand-Grip Dynamometry (composite z-score) , Baseline. Brief summary: The goal of this observational study is to learn about the multidimensional determinants of functional health in women aged 45 to 60 years. The study will focus on the role of muscle strength, bone mineral density, body composition, physical activity, sleep quality, depressive symptoms, and menopause-related symptoms in functional health. The main questions it aims to answer are: 1. Does muscle strength contribute to functional health in women aged 45 to 60 years? 2. Does bone mineral density contribute to functional health in women aged 45 to 60 years? 3. How are physical activity, sleep quality, depressive symptoms, body composition, and menopause-related quality of life associated with functional health? Participants will: * Undergo handgrip strength measurement * Perform a 30-second chair stand test * Undergo bone mineral density and body composition assessment * Complete questionnaires about physical activity, sleep quality, depressive symptoms, menopausal symptoms, and quality of life * Provide demographic and clinical information