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Life sciences · Journal article
Journal of Indonesian Medical Laboratory and Science · September 4, 2026
Early or partial results. Treat as a signal, not a conclusion.
This uncontrolled before-after study in a community setting measured blood glucose by point-of-care testing (POCT) before and after jackfruit consumption and found a statistically significant rise (p=0.00). The mean increase was 14 mg/dL at 2 hours post-consumption, but the absence of a control group, randomization, and adjustments for acknowledged confounders (fruit ripeness, individual metabolic state) limits causal inference and generalizability.
Uncontrolled before-after observational study. Community participants; specific eligibility criteria, age, sex, diabetes status, and setting not detailed.. Intervention: Jackfruit consumption in three portion categories.
Average blood glucose rise of 14 mg/dL at 2 hours after jackfruit consumption Statistically significant difference before and after consumption (p=0.00) Magnitude of increase influenced by glycemic index, fruit ripeness, and respondent conditions
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
Clinicians should note this signals that jackfruit may cause acute postprandial glycaemia rises, but the lack of control and confounding adjustment means it does not yet define the magnitude of effect, safe portion size, or clinical relevance for diabetes management or prevention. Confirmation in a randomized, controlled design with patient-relevant outcomes is needed before practice guidance can be derived.
An uncontrolled, community-based observational study with before-after measurements showing a statistically significant effect on a surrogate endpoint (blood glucose), but lacking a comparator group, randomization, or blinding, limiting causal inference.
As stated by the source record.
Quoted from the source exactly as published.
Clinicians should note this signals that jackfruit may cause acute postprandial glycaemia rises, but the lack of control and confounding adjustment means it does not yet define the magnitude of effect, safe portion size, or clinical relevance for diabetes management or prevention. Confirmation in a randomized, controlled design with patient-relevant outcomes is needed before practice guidance can be derived.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
Background: Diabetes mellitus is a global health problem that continues to rise, with projections reaching 700 million cases by 2045. In Indonesia, this disease is the third leading cause of death. Diabetes mellitus is a metabolic disorder characterized by hyperglycemia due to insulin deficiency or dysfunction. DM is classified into type 1, type 2, other types, and gestational diabetes. Type 1 DM occurs due to autoimmune destruction of pancreatic beta cells, whereas type 2 DM arises from insulin resistance and decreased insulin production. Major risk factors include unhealthy diets, fast food consumption, physical inactivity, obesity, stress, age, and family history. Lifestyle changes have also contributed to the increased prevalence of DM, particularly due to sedentary behavior. Jackfruit, as a fruit with a medium–high glycemic index, has the potential to raise blood glucose levels. This study was conducted to assess the effect of jackfruit consumption on blood glucose using the POCT method as a rapid detection tool to reduce the risk of complications and death due to DM. Objectives: observing the increase in glucose levels before and after consuming jackfruit. Materials and Methods: The study was conducted through structured interviews and blood glucose measurements using POCT before and after jackfruit consumption with three portion categories. Data were recorded based on the number of fruits consumed. Data processing was carried out using Excel and SPSS, with normality tests performed to determine the use of either the Paired Sample T-Test or the Wilcoxon test, depending on the data distribution. Results: The study showed that jackfruit consumption caused a significant increase in blood glucose levels, with an average rise of 14 mg/dL after 2 hours. Analysis using POCT, normality tests, and the Wilcoxon test indicated a significant difference before and after consumption. The magnitude of the increase was influenced by the glycemic index, fruit ripeness, and the respondents’ conditions. Conclusions: Based on the findings of this study, it can be concluded that the results showed a p-value of 0.00, indicating a statistically significant difference. This means that consuming jackfruit can increase blood glucose levels.
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