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Life sciences · Preprint
arXiv · September 29, 2026
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Self-supervised learning (SSL) by predicting in latent space, without generating the input data itself, learns highly abstract, useful representations. Intuitively, this success is often attributed to its ability to discard nuisance information that is irrelevant to prediction. However, this poses a conundrum: both stochastic variation in a prediction-relevant latent signal and true nuisance make observations partly unpredictable; how could they be distinguished? Surprisingly, we prove that common SSL methods can achieve exactly this, by implicitly instantiating a latent-variable model with stochastic dynamics and observation-private nuisance. We trace their ability to recover the stochastic signal to two complementary principles: Predictive mutual information maximization ensures that representations retain the information needed for prediction, while latent distribution matching constrains how this information is encoded, thereby making the retained signal identifiable. We confirm this identifiability result in simulations for Gaussian predictors, which recover the true signal up to an affine transformation even in dynamic, nuisance-laden environments.