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Life sciences · Interventional Study
ClinicalTrials.gov · September 23, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT06094192). This is a study registration, not published results. Lead sponsor: Boston University Charles River Campus. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 204 participants (ESTIMATED). Conditions: Alzheimer Disease. Interventions: DEVICE: High definition transcranial electrical current stimulation. Primary outcome measures: Memory performance (active stimulation condition) , Time Frame: Memory performance data is collected during active brain stimulation and reported 1 year later; Memory performance (sham stimulation condition) , Time Frame: Memory performance data is collected during sham brain stimulation and reported 1 year later. Brief summary: The investigators will evaluate the theory that Alzheimer's disease-related memory impairment derives from the inefficient orchestration of rhythmic activity at the level of large-scale cortical networks. The results as expected to elucidate AD-related pathophysiology and set groundwork for the development of drug-free interventions for improving memory in AD and related dementias.