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Life sciences · Interventional Study
ClinicalTrials.gov · September 17, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT06275217). This is a study registration, not published results. Lead sponsor: The Hong Kong Polytechnic University. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 198 participants (ACTUAL). Conditions: Mood Disorders. Interventions: BEHAVIORAL: Mindfulness-based yoga program; OTHER: Psychoeducation. Primary outcome measures: Edinburgh Postnatal Depression Scale , Baseline, 10 weeks, 6 months and 1 year follow-ups.. Brief summary: This is a parallel-group randomized controlled trial. A total of 198 postpartum women with depressive symptoms (EPDS scores≥8 at baseline) will be recruited and randomized into two groups: 10-week mindful yoga intervention and 10-week psychoeducation program. Clinical assessment of depression, self-report questionnaires and salivary cortisol tests will be performed at baseline, after 10-week intervention, and at 6-month and 12-month follow-ups. The investigators expected that the mindful yoga intervention will reduce depression after 10 weeks compared to psychoeducation. The mindful yoga intervention will further reduce anxiety, stress, improve quality of life and sleep, and steepen diurnal cortisol slopes. These effects will be maintained for at least six months.