Life sciences · Preprint
arXiv · September 14, 2026
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Flow-matching diffusion models have recently emerged as a strong paradigm for high-fidelity visual generation. However, their prohibitively high fine-tuning cost limits scalability to downstream tasks. While Low-Rank Adaptation (LoRA) combined with spectral initialization has demonstrated accelerated convergence and improved performance in autoregressive language models by better aligning gradient directions, we find that it fails to deliver similar gains in diffusion fine-tuning, often yielding marginal or even negative improvements over vanilla LoRA.We attribute this discrepancy to a fundamental mismatch between LoRA's low-rank parameterization and the intrinsically high-rank gradients induced by the flow-matching objective. In particular, stochastic timestep sampling introduces directionally heterogeneous gradient signals across training steps, leading to misaligned updates under low-rank constraints.To address this issue, we propose Prism-LoRA,a Principal-timestep Restricted Init via Sparse Matrix-decomposition framework that improves gradient alignment during fine-tuning. Our method consists of two key components: (i) principal timestep selection, which restricts initialization gradients to a subset of dominant timesteps to suppress effective gradient rank, and (ii) principal channel filtering, which removes task-irrelevant channels, enabling the one-step spectral initialization gradient to better align with the long-horizon optimization trajectory. Extensive experiments demonstrate that our method consistently improves both convergence speed and final performance across multiple diffusion fine-tuning benchmarks, including subject-driven generation, controllable generation, and deblurring, achieving not only performance improvement but also earlier stages of convergence over baseline LoRA and other spectral-init methods.