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Life sciences · Interventional Study
ClinicalTrials.gov · September 14, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT03106441). This is a study registration, not published results. Lead sponsor: Nantes University Hospital. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 100 participants (ACTUAL). Conditions: Severe Obesity Design as BMI > 35kg/m2. Interventions: DEVICE: High flow oxygen therapy by nasal cannula. Optiflow®; DEVICE: Facial mask oxygenation in BIPAP ventilation. Primary outcome measures: Expired fraction of oxygen at the end of intubation , 2 minutes. Brief summary: Oro-tracheal intubation in operating room in obese patients with BMI \> 35kg/m2 remains a critical event. The aim of this study is to determine whether Nasal High Flow Therapy by nasal cannula Optiflow® is more efficient than the BIPAP preoxygenation before orotracheal intubation after crash induction in obese patients