Life sciences · Preprint
arXiv · September 6, 2026
Early or partial results. Treat as a signal, not a conclusion.
This preprint characterizes how weight-only quantization (INT8 and NF4) affects the reliability and cost of inference-time activation steering across open-weight language models. Sentiment steering appears robust to quantization, but reasoning-length steering exhibits asymmetric dose-response with stepwise failures in the shortening direction, and baseline capability shifts can exceed steering effects—yet steering vectors themselves remain geometrically aligned with unquantized versions.
Systematic controlled study across multiple models and quantization schemes with preregistered analysis. Four open-weight language models (Mistral and three others, 7–9B parameters); no human subjects or clinical populations studied.. Intervention: Inference-time activation steering under INT8 and NF4 weight-only quantization. Compared with: FP16 (unquantized) baseline and steering-free quantized models.
Sentiment steering survives quantization with pooled INT8 contrast of −0.010 (90% CI [−0.026, +0.007]), rated Equivalent under preregistered three-label rule NF4 sentiment steering remains Inconclusive at −0.017 (90% CI [−0.067, +0.033]) Reasoning length shortening exhibits step-function failure with only 12–30% shortening (model-dependent) before discontinuous collapse
Reasoning length shortening exhibits step-function failure with only 12–30% shortening (model-dependent) before discontinuous collapse
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This is a preprint systematic study of an understudied technical interaction (activation steering under quantization) with novel methodological contributions, but it examines proxy behavioral targets in simulated deployments rather than clinical or real-world outcomes, and has not undergone peer review.
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Inference-time activation steering enables behavioral control of large language models without parameter modification, while post-training quantization reduces memory and compute costs for deployment. Despite their growing convergence in practice, the interaction between these two techniques remains uncharacterized. We systematically study activation steering under weight-only quantization (INT8 and NF4) across four open-weight 7-9B models and two behavioral targets: judged sentiment and judge-free reasoning length. Using an iso-effect framework that compares capability costs at matched behavioral effect, we find that sentiment steering survives quantization intact. After correcting a GSM8K parser artifact with a uniform v2.3.1 rescore, the pooled INT8 contrast is -0.010 (90% CI [-0.026, +0.007]), descriptively Equivalent under the preregistered three-label rule, while NF4 remains Inconclusive at -0.017 ([-0.067, +0.033]). In contrast, reasoning length exhibits a surprising asymmetric dose-response: lengthening is graded but terminates in cap-runaway and collapse, while shortening is a step function with only 12-30% shortening (model-dependent) before discontinuous failure. We expose a methodological pitfall: the naive iso-effect ladder anchors on the collapse floor for floor-bounded targets, and we introduce a censored construction that restores interpretable crossings. We also quantify a substantial baseline capability shift for Mistral-NF4 (0.545 to 0.365 GSM8K at alpha=0), demonstrating that compression can dominate the steering intervention. Despite this, steering vectors remain highly collinear with their FP16 siblings (cosine similarity 0.989-0.998 for INT8, 0.945-0.990 for NF4), confirming that the behavioral direction survives quantization even when the cost structure does not. All code and data are released.
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