Life sciences · Preprint
arXiv · September 11, 2026
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Instruction-tuning datasets for large language models (LLMs) are often large, redundant, and imbalanced, limiting efficient adaptation. Naive large-batch fine-tuning repeatedly includes overrepresented sample groups while weakly covering underrepresented but informative ones, especially under data parallelism (DP) across multiple GPUs. We propose CluSTER, a Cluster-aware balanced Sampling framework for Training Efficient data Reduction in DP instruction tuning. CluSTER curates a representative reduced dataset through gradient-space clustering and DP-aware balanced allocation, ensuring dual-level coverage across clusters and workers, while preserving the original data distribution by weighted update. As a result, CluSTER reduces redundant computation and improves training stability without compromising model quality. Across multiple instruction-tuning datasets, CluSTER reduces training time by up to 69.6% with almost no accuracy loss compared to prior sampling and data reduction methods. Code is available at https://github.com/kaist-dmlab/CluSTER.