Life sciences · Preprint
arXiv · October 6, 2026
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Low-rank quantization error compensation (LQEC) recovers the accuracy lost under aggressive weight quantization by attaching a closed-form rank-$r$ adapter beside each frozen quantized weight, without any training. We show that existing compensators are limited by two shared simplifications. They calibrate symmetrically, evaluating the full-precision and compensated weights on the same activation, which yields a compensation target that is inherently high-rank -- so a fixed rank budget captures only a small fraction of it. And they minimize only the second-order term of the loss, although the compensated model is not stationary: a first-order descent direction larger than the applied compensation itself remains in every layer, and no reconstruction objective can absorb it. We propose a two-stage closed-form framework that removes both simplifications. Stage 1 aligns each layer's output with the full-precision model under a Fisher-weighted asymmetric objective, concentrating the rank budget on a rank-compressible target. Stage 2 re-measures statistics on the compensated model and applies a rank-constrained natural-gradient step that absorbs the remaining first-order signal. Every adapter is the result of a single truncated SVD; backward passes serve only to collect statistics. At 2 bits under QuIP#, our method reduces WikiText-2 perplexity from 12.43 to 10.26 on Qwen3-8B and from 21.11 to 13.22 on Qwen3-4B. On the held-out C4 corpus, it recovers 51% and 84% of the gap to FP16, versus 31% and 63% for the strongest baseline, with consistent gains in the seven-task zero-shot average, at higher bit-widths, and under a distinct quantizer.