Life sciences · Phase 2/3 Trial
ClinicalTrials.gov · October 23, 2026
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Phase 2/3 Trial.
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Registry record from ClinicalTrials.gov (NCT07891156). This is a study registration, not published results. Lead sponsor: McGill University Health Centre/Research Institute of the McGill University Health Centre. Recruitment status: RECRUITING. Phase: PHASE2, PHASE3. Study type: INTERVENTIONAL. Enrollment: 40 participants (ESTIMATED). Conditions: Type 1 Diabetes, Overweight , Obesity. Interventions: DRUG: Semaglutide; DRUG: Placebo. Primary outcome measures: Change in lean mass , Baseline to 24 weeks of study drug use. Brief summary: The goal of this 24 week double-blinded, randomized, parallel controlled clinical trial is to learn how semaglutide affects body composition in adults with type 1 diabetes and overweight/obesity. The main question to answer is: What effect does Semaglutide have on body composition in adults with type 1 diabetes and overweight/obesity compared to a placebo? Around 40 participants will: * Be randomly assigned to receive semaglutide or a placebo. * Self-administer the treatment drug once per week for 24 weeks. * Complete a series of tests, measurements and questionnaires throughout the study duration. * Attend a remote follow-up visit 4 weeks after the treatment is complete.