Loading
Life sciences · Review
Trends in Immunotherapy · October 16, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Review.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
The advent of immune checkpoint inhibitors (ICIs) has revolutionized cancer treatment, offering an effective therapeutic option for advanced cancers. However, their widespread use has led to the occurrence of immune-related adverse events (irAEs), including pulmonary toxicity. ICI-induced pulmonary toxicity represents one of the most relevant irAEs because of its heterogeneous clinical and radiological presentation and its potential life-threatening course. Computed tomography (CT) is the imaging modality of choice for evaluating lung irAEs and the specific patterns associated with ICI-induced pneumonitis. A literature search of the PubMed and Scopus databases was conducted to identify studies published over the past decade investigating pulmonary adverse effects associated with ICI therapy. Relevant studies were reviewed with particular attention to the clinical and radiological features of ICI-induced pulmonary toxicity, including the main CT patterns of pneumonitis and the emerging applications of radiomics and machine learning. This narrative review aims to provide a comprehensive overview of the current evidence on the radiological manifestations of lung irAEs, with particular emphasis on CT findings and radiomics and its potential role in the prediction and diagnosis of lung irAEs. Ultimately, this research highlights the importance of a multidisciplinary approach in the diagnosis and management of ICI-induced pulmonary toxicity, with radiologists playing a critical role in identifying and monitoring these potentially life-threatening events.