Life sciences · Interventional Study
ClinicalTrials.gov · October 23, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT05731791). This is a study registration, not published results. Lead sponsor: Weill Medical College of Cornell University. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 17 participants (ACTUAL). Conditions: Breast Cancer. Interventions: RADIATION: Radiation Therapy to partial breast. Primary outcome measures: Comparing local recurrence rates between patients receiving Standard CT radiation therapy (ARM1) and MRI-based radiation therapy (ARM 2) , 24months. Brief summary: The Investigators are investigating the potential role of MRI-guided Radiation Therapy for patients receiving breast radiotherapy in the prone position with a MRI-Linac radiotherapy system, the Precision Prone Irradiation (PPI) technique. Hypothesis: The investigators would like to hypothesize that breast radiation therapy using MRI-guided system including the MRI-Linac (Arm 2) is comparable to the current standard of treatment using conventional CT-based system (Arm 1), in terms of local control of the disease at 2 year time point.