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Life sciences · Observational Study
ClinicalTrials.gov · October 16, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT07877090). This is a study registration, not published results. Lead sponsor: Duzce University. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 60 participants (ESTIMATED). Conditions: Obesity (BMI>30), General Anesthesia. Interventions: OTHER: Frontal Electroencephalography Monitoring. Primary outcome measures: Difference in Bilateral Spectral Edge Frequency Between BMI Groups During General Anesthesia , From induction of general anesthesia until the end of surgery. Brief summary: This prospective observational study aims to compare frontal electroencephalographic (EEG) spectral dynamics between patients with obesity and normal weight undergoing general anesthesia. The primary objective is to evaluate whether changes in frontal alpha power around propofol-induced loss of consciousness differ between the two BMI groups. Secondary objectives include comparing changes in delta power, the alpha/delta power ratio, and frontal alpha asymmetry around loss of consciousness, as well as evaluating EEG spectral dynamics throughout the intraoperative period. Anesthetic management will be determined by the attending anesthesiologist according to routine clinical practice, without intervention by the study investigators.