Life sciences · Preprint
arXiv · September 3, 2026
Posted before peer review. The findings may change or fail to hold.
This is an unpublished preprint describing PreferenceEKF, a computational method for efficient active learning of reward models from human preferences using subspace Bayesian filtering. The authors report improved sample efficiency, runtime, and scalability on standard reinforcement learning benchmarks compared to other Bayesian deep learning approaches, but the work is algorithmic and has not been peer-reviewed or validated in human-in-the-loop settings.
Preprint. Intervention: PreferenceEKF: sequential Bayesian filtering of reward model parameters in a low-dimensional subspace, with active preference query acquisition. Compared with: Other Bayesian deep learning approaches for uncertainty quantification in reward learning.
PreferenceEKF achieves better sample efficiency and runtime scalability than other Bayesian deep learning approaches on D4RL and V-D4RL benchmarks Learned reward models lead to competitive offline reinforcement learning policy performance Method demonstrates improved calibration compared to baseline Bayesian approaches
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This is an unrefereed arXiv preprint presenting a novel computational method for reward model training, not a clinical trial or peer-reviewed evidence synthesis; it reports algorithmic improvements but has not undergone peer review.
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Reinforcement learning from human feedback (RLHF) has emerged as a powerful yet sample-inefficient approach for learning reward models from human preferences, making active learning a critical component in synthesizing informative preference queries. However, effective uncertainty quantification required for active learning remains a key challenge for large neural network reward models. In this paper, we introduce PreferenceEKF, a sample-efficient approach that tracks reward model uncertainty by framing active preference learning as a sequential Bayesian filtering problem. Instead of relying on computationally prohibitive posterior inference over the full neural network parameter space, our method performs sequential inference via an extended Kalman filter within a low-dimensional parameter subspace, continuously updating the reward model posterior as new preference queries arrive. Our approach enables scalable sampling of neural network parameters to efficiently compute acquisition functions for active reward learning. Experiments on the D4RL and V-D4RL benchmarks demonstrate that our approach achieves better sample efficiency, runtime, scalability, and calibration compared to other Bayesian deep learning approaches, and the learned reward models lead to competitive offline reinforcement learning policy performance. This highlights the potential of scalable Bayesian methods for preference-based reward modeling in RLHF. Our code is available at https://github.com/yutaizhou/bnn_pref.
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