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Life sciences · Observational Study
ClinicalTrials.gov · October 21, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT07713719). This is a study registration, not published results. Lead sponsor: Coventry University. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 50 participants (ESTIMATED). Conditions: Heart Failure. Interventions: OTHER: Study Assessment. Primary outcome measures: Change in Arterial stiffness measured by Pulse wave velocity (PWV) using SphygmoCor , Up to 12 week; Change in Endothelial Function Measured by Laser Doppler Flowmetry (LDF) , Up to 12 weeks. Brief summary: Heart Failure (HF) is a global condition affecting at least 26 million people worldwide. Despite advances in treatment, HF patients continue to experience poor health outcomes. This study aims to improve understanding of the role of blood vessels in people with heart failure. The study will assess how arterial stiffness (how stiff blood vessels are) and endothelial function (how well the lining of blood vessels functions) change over time and respond to treatments received as part of routine clinical care. Blood vessel function and heart performance will be assessed at three time points: * At baseline (when Patients are first diagnosed with heart failure). * After completing 4 ± 2 weeks of heart-failure medicines prescribed to patients as part of their routine clinical care. * After completion of cardiac rehabilitation program as a part of their routine clinical care. All assessments are non-invasive.