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Life sciences · Observational Study
ClinicalTrials.gov · September 15, 2026
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Observational Study.
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Registry record from ClinicalTrials.gov (NCT07819708). This is a study registration, not published results. Lead sponsor: Benha University. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 60 participants (ACTUAL). Conditions: Sepsis, Septic Shock. Primary outcome measures: 28-Day All-Cause Mortality , From intensive care unit admission through 28 days. Brief summary: Sepsis and septic shock are serious conditions associated with a high risk of organ dysfunction and death. Simple laboratory-based markers may help identify critically ill patients who are at greater risk of poor outcomes. This prospective observational cohort study compared the prognostic value of the neutrophil-to-lymphocyte ratio and the lactate-to-albumin ratio in adult patients with sepsis or septic shock admitted to the Surgical Intensive Care Unit at Benha University Hospital. A total of 60 participants were enrolled and followed for 28 days. The study evaluated the relationship of both laboratory ratios with 28-day mortality and compared their ability to predict mortality. Intensive care unit length of stay and progression of organ dysfunction were also assessed.