Loading
Life sciences · Interventional Study
ClinicalTrials.gov · October 23, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Interventional Study.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT03215849). This is a study registration, not published results. Lead sponsor: Cardiff and Vale University Health Board. Recruitment status: COMPLETED. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 10 participants (ACTUAL). Conditions: Heart Failure. Interventions: DEVICE: CRT-pacemaker device set to Routine Medical Therapy; DEVICE: CRT-pacemaker device set to Routine Medical Therapy + LVP; DEVICE: CRT-pacemaker device set to Routine Medical Therapy + BiVP. Primary outcome measures: Change in septal radius of curvature (corrected for LV area) between rest and peak exercise on stress echocardiography across the three pacing states. , 12 weeks. Brief summary: A random-order cross-over pilot trial of a CE marked device (pacemaker) outside its current intended purposes. The study will comprise 10 patients. Recruitment of patients will take place from The University Hospital of Wales (Cardiff \& Vale University Health Board \[CVUHB\]). All patients recruited will have septal flattening during exercise demonstrated using contrast stress (exercise) echocardiography. All 10 patients will be implanted with a CRT-pacemaker device and will be tested on all three of the following settings on separate visits (with a gap of up to 5 days between visits) in random order: Routine Medical Therapy Routine Medical Therapy + LVP Routine Medical Therapy + BiVP