Life sciences · Phase 1/2 Trial
ClinicalTrials.gov · October 23, 2026
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Phase 1/2 Trial.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT06874621). This is a study registration, not published results. Lead sponsor: Voyager Therapeutics. Recruitment status: ACTIVE_NOT_RECRUITING. Phase: PHASE1, PHASE2. Study type: INTERVENTIONAL. Enrollment: 52 participants (ESTIMATED). Conditions: Alzheimer's Disease (AD). Interventions: DRUG: VY7523; DRUG: Placebo Comparator. Primary outcome measures: Characterization of the safety and tolerability of VY7523 in participants with early AD , Cohorts 1 and 2: up to 6 months Cohort 3: up to 12 months. Brief summary: This study is to be conducted in participants with early Alzheimer's Disease to test VY7523, a new drug being researched for treatment of Alzheimer's Disease. This study will look at how safe the drug is and how it works in the brain. It was first tested in normal, healthy participants who volunteered to participate. The study will look at three different dose levels, starting with the lowest dose first and moving to higher doses and more participants after safety has been reviewed by doctors and researchers. Some patients will receive drug while others will receive placebo. This will help to better compare how the drug works between participants receiving drug and placebo. The study will last up to 6 months for the lower dose groups and 12 months for the highest dose group.