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Timing of exercise / Overweight , Obesity / Prediabetes · Interventional Study
ClinicalTrials.gov · September 11, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned clinical trial testing whether exercise timing (morning vs. evening) based on individual chronotype improves insulin sensitivity in adults with prediabetes. No results are yet reported in this registry record; the study remains in recruitment phase and the design and sample size are small, limiting the strength of any eventual conclusion.
Interventional, Randomized, Crossover, Single masking, Treatment purpose. Prediabetes, Overweight , Obesity; age from 19 Years; to 75 Years. Intervention: AM exercise; PM exercise. Compared with: Control — Active Comparator. n = 28. 1 site: Germany.
This is a planned clinical trial testing whether exercise timing (morning vs. evening) based on individual chronotype improves insulin sensitivity in adults with prediabetes. No results are yet reported in this registry record; the study remains in recruitment phase and the design and sample size are small, limiting the strength of any eventual conclusion.
This is a registry record with no posted results; efficacy and safety data are not yet available.
If completed and positive, this trial could inform timing of exercise prescription in prediabetes management. However, the small sample and lack of active comparator limit the generalizability of any findings to routine clinical practice.
This is a clinical trial registration with no posted results; it describes a planned interventional study with a small sample examining a mechanistic hypothesis about exercise timing and insulin sensitivity in prediabetes.
As stated by the source record.
Quoted from the source exactly as published.
If completed and positive, this trial could inform timing of exercise prescription in prediabetes management. However, the small sample and lack of active comparator limit the generalizability of any findings to routine clinical practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07389005). This is a study registration, not published results. Lead sponsor: German Diabetes Center. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 28 participants (ESTIMATED). Conditions: Prediabetes, Overweight , Obesity. Interventions: BEHAVIORAL: Timing of exercise; BEHAVIORAL: Timing of exercise; BEHAVIORAL: Control. Primary outcome measures: Insulin sensitivity , 12 to 24 hours post-exercise intervention. Brief summary: The goal of this clinical trial is to find out whether exercising at the right time of day, based on a person's natural body clock, leads to greater health benefits in people living with prediabetes. The main question it aims to answer is whether doing a single session of exercise in the morning or in the evening affects how the body handles sugar differently in adults with prediabetes who have an extreme natural body clock. This will be done by comparing three conditions (no-exercise, morning exercise, and evening exercise) within the same participant. Each condition will be tested on a different day, with at least 14 days between the test days. During the no-exercise test days, participants will come to the study centre and will only be allowed to do sedentary activities (e.g. office work, reading, or screen time). During the morning exercise test days, participants will perform an exercise session at 9:00 am that involves short periods of very hard effort followed by short rest periods. Whereas for the evening exercise test days, the same type of exercise will be performed at 5:00 pm.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.