Life sciences · Preprint
arXiv · September 24, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Preprint.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Selective classification enables a model to abstain from predictions on uncertain instances, but existing approaches typically reject them through confidence scores, predefined coverage constraints or instance-level distance measures. These approaches may overlook the collective geometric structure of difficult samples in learned representation spaces. We propose Guided Clustering-based Uncertain Learning (GCUL), a geometric-guided selective classification framework that identifies misclassified and ambiguous instances as a potential confusion attractor in the representation space. GCUL uses a three-phase procedure to initialize, cluster, and explicitly relabel this uncertain region, allowing the rejection boundary to emerge from the underlying representation geometry rather than from a prescribed rejection rate. We further derive a selectivity score and a geometric sufficient condition that characterizes when rejection can provide positive operational utility, enabling pre-deployment feasibility assessment. GCUL improves DistilBERT accuracy from 89.37 percent to 94.98 percent with less than 9 percent rejection. Beyond accuracy, our selectivity score correctly pre-detects the only dataset (GoEmotion) where all baselines fail, and controlled simulations yield 6.1 percent Type-I and 0 percent Type-II errors, validating the sufficient condition's conservatism. These results suggest that collective representation geometry provides a useful alternative perspective for selective prediction.