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Life sciences · Interventional Study
ClinicalTrials.gov · September 17, 2026
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Interventional Study.
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Registry record from ClinicalTrials.gov (NCT07210255). This is a study registration, not published results. Lead sponsor: Magnus Medical. Recruitment status: RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 192 participants (ESTIMATED). Conditions: Postpartum Depression (PPD). Interventions: DEVICE: SAINT Neuromodulation System; DEVICE: Sham SAINT Stimulation. Primary outcome measures: The change in depression symptom severity, assessed using the Montgomery-Åsberg Depression Rating Scale (MADRS), from baseline to 5 days post-treatment, which will be compared between the acute active SAINT and sham arms. , Baseline and 5 days post-acute treatment. Brief summary: This study is a large, multi-site clinical trial testing whether Stanford Accelerated Intelligent Neuromodulation Therapy (SAINT), a fast-acting form of repetitive transcranial magnetic stimulation (rTMS), can more effectively reduce symptoms of postpartum depression (PPD) compared to a sham treatment. It will enroll 192 women within 12 months postpartum who are experiencing depression, and will track their progress for up to 12 months. The trial's main goal is to see if SAINT leads to reduction in depression severity in women with postpartum depression.