Loading
Life sciences · Interventional Study
ClinicalTrials.gov · November 9, 2026
No summary has been generated for this record yet. What follows is drawn from its source metadata only.
Interventional Study.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
The source did not state who this applies to in practice.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
This record has not been graded across any dimension yet. Treat the label above as provisional and read the source.
What is missing. This record has no bottom line, key findings, reported figures, evidence dimensions. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07925515). This is a study registration, not published results. Lead sponsor: Universidad Internacional Isabel I de Castilla. Recruitment status: NOT_YET_RECRUITING. Phase: NA. Study type: INTERVENTIONAL. Enrollment: 36 participants (ESTIMATED). Conditions: Heart Failure Reduced Ejection Fraction. Interventions: BEHAVIORAL: HIIT + Strength Training; BEHAVIORAL: MICT + Strength Training. Primary outcome measures: Recruitment Rate , From the start of recruitment to the end of the first 9 months of recruitment.; Acceptance of Randomisation , From screening and referral throughout the recruitment period.; Participant Retention , At the end of the 12-week intervention.; Adherence to Prescribed Exercise Sessions , Throughout the 12-week intervention.; Fidelity to the Assigned HIIT Intervention , Throughout the 12-week intervention.; Completeness of Post-Intervention MLHFQ Data , At the end of the 12-week intervention.; Exercise-Related Adverse Events , Throughout the 12-week intervention and the study period in which exercise-related adverse events are monitored.. Brief summary: Heart failure is associated with impaired health-related quality of life and reduced exercise capacity. Women remain under-represented in cardiac rehabilitation research, and evidence comparing high-intensity interval training (HIIT) with moderate-intensity continuous training (MICT) in women with heart failure is limited. HIIT-WHEF is a prospective, single-centre, randomised pilot feasibility trial involving 36 women aged 18 years or older with heart failure and a left ventricular ejection fraction below 50%. Participants will be randomly allocated in a 1:1 ratio to a 12-week supervised cardiac rehabilitation programme incorporating either HIIT or MICT. Both groups will also undertake individualised resistance training. The primary objectives are to assess the feasibility and safety of conducting the randomised trial, including recruitment, acceptance, retention, adherence, intervention fidelity, completeness of outcome data and exercise-related adverse events. Health-related quality of life, assessed using the Minnesota Living with Heart Failure Questionnaire (MLHFQ), is the key clinical outcome of interest. Peak oxygen uptake, left ventricular ejection fraction and biomarkers will be assessed as exploratory clinical outcomes. The study is designed to inform the planning of a future adequately powered confirmatory trial. It is not intended to establish definitive evidence of the superiority of HIIT over MICT.