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Life sciences · Phase 1 Trial
ClinicalTrials.gov · October 9, 2026
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Phase 1 Trial.
No findings were extractable from the material analysed.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
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Registry record from ClinicalTrials.gov (NCT05556473). This is a study registration, not published results. Lead sponsor: Barbara Ann Karmanos Cancer Institute. Recruitment status: COMPLETED. Phase: PHASE1. Study type: INTERVENTIONAL. Enrollment: 20 participants (ACTUAL). Conditions: Intracranial Glioma, Metastatic Brain Tumor, Breast Cancer, Neuroendocrine Tumors, Rectal Cancer. Interventions: DRUG: 1-(2-[18F]FLUOROETHYL)-L-Tryptophan. Primary outcome measures: The percent difference in tracer uptake values between the tumor mass and the background (non-tumor tissue) , During procedure (from right after tracer injection to 1-hour post-injection); Correlation between the 1-(2-[18F]fluoroethyl)-L-tryptophan tracer uptake values and the tracer transport rates measured in the same breast tumor tissue. , During procedure (from right after tracer injection to 1-hour post-injection). Brief summary: Imaging procedures such as 1-(2-\[18F\]FLUOROETHYL)-L-Tryptophan PET/CT in patients with cancers may help doctors assess a patient's response to treatment and help plan the best treatment in the future. The purpose is to see if there can be a better differentiation of tumor and non-tumor tissue where the tumor tissue has a higher uptake of Tryptophan.