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Pulmonary Vascular Disease / Heart Failure · Observational Study
ClinicalTrials.gov · August 20, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a planned observational study registered at ClinicalTrials.gov to evaluate whether non-invasive contrast echocardiography-derived pulmonary blood volume can serve as a surrogate for invasive pulmonary artery wedge pressure during exercise in patients with heart failure and pulmonary vascular disease. No results are yet reported in this registry record.
Observational. Heart Failure, Pulmonary Vascular Disease; age from 18 Years. Intervention: Contrast echocardiography during exercise to measure pulmonary blood volume and pulmonary vascular capacitance.. Compared with: Invasive pulmonary artery wedge pressure (PAWP) during exercise.. n = 800. 1 site: United States.
This is a planned observational study registered at ClinicalTrials.gov to evaluate whether non-invasive contrast echocardiography-derived pulmonary blood volume can serve as a surrogate for invasive pulmonary artery wedge pressure during exercise in patients with heart failure and pulmonary vascular disease. No results are yet reported in this registry record.
No data on efficacy, safety, or diagnostic accuracy are available.
Once results are published, findings may inform whether contrast echocardiography can replace invasive haemodynamic assessment during exercise in pulmonary vascular and heart failure evaluation. Current registry entry does not yet support clinical decision-making.
This is a recruiting observational registry study with no posted results; it represents planned research rather than evidence of efficacy or safety.
As stated by the source record.
Quoted from the source exactly as published.
Once results are published, findings may inform whether contrast echocardiography can replace invasive haemodynamic assessment during exercise in pulmonary vascular and heart failure evaluation. Current registry entry does not yet support clinical decision-making.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT06195059). This is a study registration, not published results. Lead sponsor: Mayo Clinic. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 800 participants (ESTIMATED). Conditions: Heart Failure, Pulmonary Vascular Disease. Primary outcome measures: Pulmonary Vascular Capacitance at Rest , Baseline; Pulmonary Vascular Capacitance During Exercise , Baseline. Brief summary: The purpose of this study is to evaluate whether pulmonary blood volume (PBV) derived from contrast echocardiography can serve as a non-invasive surrogate for invasive pulmonary artery wedge pressure (PAWP) during exercise. Also, to compare changes in PBV with exercise in patients with and without heart failure and pulmonary vascular disease.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.