Postoperative Nausea and Vomiting (PONV) · Observational Study

Early Postoperative Pain After Cardiac Surgery

ClinicalTrials.gov · September 4, 2026

Preliminary Why this matters to you Expert discussion

Early or partial results. Treat as a signal, not a conclusion.

AI Summary

This is a recruiting observational study registration that has not yet reported results. The study aims to examine associations between patient characteristics, preoperative psychological factors, and surgical/anesthetic factors with postoperative pain severity in the first 24 hours after cardiac surgery. No evidence of efficacy or harm can be drawn from this registry record.

What was studied

Observational. Postoperative Nausea and Vomiting (PONV); age from 18 Years. Intervention: Cardiac Surgery Cohort. n = 99. 1 site: Turkey (Türkiye).

Key findings

Safety

Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.

Who this may help

The source did not state who this applies to in practice.

Plain-language summary

This is a registry record for a recruiting observational study with no results posted; it describes planned methods and enrollment only, not outcomes or findings.

Study design

As stated by the source record.

MethodsCohort model. Retrospective time perspective. Primary outcome measure: Mean Postoperative Pain Score During the First 24 Hours (assessed at First 24 hours after surgery)

DesignObservational

PopulationPostoperative Nausea and Vomiting (PONV); age from 18 Years

Sample size99

InterventionCardiac Surgery Cohort

Setting1 site: Turkey (Türkiye)

Reported figures

Quoted from the source exactly as published.

Planned enrollment99

Primary outcome measureMean Postoperative Pain Score During the First 24 Hours

Primary outcome timepointFirst 24 hours after surgery

Caveats

This is a registry record only; no results are reported and recruitment is ongoing.
Retrospective design with potential for medical record documentation bias and missing data.
No comparator group or randomization; only associations will be examined, not causal effects.
Study has not been completed; no outcomes, effect sizes, or statistical analyses are available.

Evidence assessment

Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.

Study design

limited

Observational retrospective medical record review; no control group or intervention.

Directness

strong

Primary outcome is direct clinical measure: mean postoperative pain score first 24 hours.

Consistency

insufficient

No results reported; consistency cannot be assessed from registry record alone.

Risk of bias

limited

Retrospective design with potential for selection and documentation bias; no blinding.

Sample adequacy

limited

Estimated 99 participants; small for multivariable analysis of multiple predictors.

What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.

Source abstract

Registry record from ClinicalTrials.gov (NCT07804732). This is a study registration, not published results. Lead sponsor: Meltem Ceylan Delice. Recruitment status: RECRUITING. Study type: OBSERVATIONAL. Enrollment: 99 participants (ESTIMATED). Conditions: Postoperative Nausea and Vomiting (PONV). Primary outcome measures: Mean Postoperative Pain Score During the First 24 Hours , First 24 hours after surgery. Brief summary: This observational study will evaluate factors that may be associated with pain during the first 24 hours after open heart surgery. The study will include adult patients who underwent coronary artery bypass grafting (CABG), heart valve surgery, or combined cardiac surgery. Researchers will retrospectively review existing medical records to examine whether patient characteristics, preoperative anxiety and depression, and factors related to surgery and anesthesia are associated with postoperative pain. The study will also evaluate postoperative nausea and vomiting and the need for additional pain medication. No treatment or intervention will be assigned to participants as part of this study. Study data will be collected retrospectively from existing medical records.

Follow from this

Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.

Meltem Ceylan DeliceNCT07804732Postoperative Nausea and Vomiting (PONV)