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Postmastectomy Lymphedema / manual lymphatic drainage · Observational Study
ClinicalTrials.gov · September 9, 2026
Early or partial results. Treat as a signal, not a conclusion.
This is a completed but unpublished observational study registration examining whether ultrasound measurements of deep fascial thickness can predict treatment response to manual lymphatic drainage in postmastectomy lymphedema. No results are reported in the registry record, so the strength and direction of any association remain unknown.
Observational. Postmastectomy Lymphedema; Female; age from 18 Years. Intervention: manual lymphatic drainage. n = 42. 1 site: Turkey (Türkiye).
This is a completed but unpublished observational study registration examining whether ultrasound measurements of deep fascial thickness can predict treatment response to manual lymphatic drainage in postmastectomy lymphedema. No results are reported in the registry record, so the strength and direction of any association remain unknown.
Safety was not reported in the material analysed. Check the source before drawing any conclusion about harm.
No results are available from this registry record. Clinicians should await publication of the findings before drawing conclusions about the predictive value of deep fascial thickness for treatment response.
This is a completed observational study registration with no results posted; the design is descriptive and exploratory, examining associations between ultrasound measurements and treatment response in a small single-arm cohort.
As stated by the source record.
Quoted from the source exactly as published.
No results are available from this registry record. Clinicians should await publication of the findings before drawing conclusions about the predictive value of deep fascial thickness for treatment response.
Graded across the dimensions that decide whether you should act, each from what the source actually supports. There is no single score, and where a dimension was not assessed it says so.
What is missing. This record has no key findings. That is a gap in the analysis, not a judgement about the study.
Registry record from ClinicalTrials.gov (NCT07810036). This is a study registration, not published results. Lead sponsor: Istanbul Physical Medicine Rehabilitation Training and Research Hospital. Recruitment status: COMPLETED. Study type: OBSERVATIONAL. Enrollment: 42 participants (ACTUAL). Conditions: Postmastectomy Lymphedema. Interventions: PROCEDURE: manual lymphatic drainage. Primary outcome measures: measurement of subcutan tissue and deep fascia thickness , 3 months. Brief summary: Research and Literature Summary / References (The research summary must not exceed 250 words and must be written in a clear, easily understandable form.) Lymphedema is a chronic and progressive disease that develops as a result of the accumulation of protein-rich fluid in the interstitial tissue following disruption of lymphatic drainage. Lymphedema of the upper extremity seen after breast cancer treatment is the most frequently encountered form, and it causes loss of function, restriction of movement, and deterioration in quality of life. Manual lymphatic drainage (MLD), a component of complex decongestive therapy (CDT), is a method of proven efficacy in reducing skin and subcutaneous tissue thickness. Duygu-Yıldız et al. (2023) demonstrated that compression applied at different pressures produced a significant reduction in skin and subcutaneous tissue thickness and accelerated the resolution of edema. High-resolution ultrasound is used as a reliable method for evaluating the skin, subcutaneous adipose tissue, and fascial structures in lymphedema. Pirri et al. (2024) reported that in patients with lymphedema there is thickening of the cutis and subcutaneous tissue, an increase in echogenicity, and structural changes in the fascial structures, and that these changes may show a regional distribution. In another study by the same research group, it was determined that in patients with lymphedema the superficial and deep fasciae are thinner compared with healthy individuals. It was emphasized that this may be an important clue regarding the role of fascial structure in the development of lymphedema. In this thesis study, the effect of MLD treatment on days 1 and 15 in patients with stage 1-2 lymphedema will be evaluated by ultrasound, and the relationship between changes in subcutaneous tissue thickness and deep fascia thickness will be investigated. The aim is thereby to objectively demonstrate the response given to treatment and to make clinical rehabilitation more individualized.
Taken from the source record, never inferred. Follow any of these and new work involving them reaches your briefing.