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Life sciences · Preprint
arXiv · September 15, 2026
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High-density surface electromyography (HD-sEMG) gesture recognition supports prosthetic control, assistive robotics, and rehabilitation, but electrode re-donning and physiological variability cause distribution shifts that degrade accuracy across sessions and subjects. Generative HD-sEMG models primarily synthesize signals for augmentation; although diffusion models enhance representation learning, prediction still relies on a separate classifier. To tie learned dynamics to the decision rule, we propose MyoFlow, the first discriminative flow-matching framework for HD-sEMG recognition across sessions and subjects. It recasts classification as anchor-tied transport: a domain-conditioned rectified flow moves encoded windows toward gesture anchors that serve as transport targets and define the nearest-anchor decision geometry, enabling zero-shot prediction without an independent head. On the Hyser dataset, MyoFlow improves mean cross-session and cross-subject accuracy over the strongest diffusion-based baseline by 4.24\% and 6.37\%, respectively, and achieves 91.71\% mean zero-shot accuracy and 97.39\% mean few-shot accuracy across multiple days on the CEMHSEY dataset.